CD4 Mouse Monoclonal Antibody [Clone ID: 8G1B12]

Specifications

Product Data
Clone Name	8G1B12
Applications	WB
Recommend Dilution	WB: 0.5 - 1 ug/mL
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Mouse monoclonal CD4 antibody was raised against a 193 amino acid recombinant protein from near the amino terminus of human CD4.
Formulation	PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	CD4 Monoclonal Antibody is immunoaffinity chromotography purified IgG.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	CD4 molecule
Database Link	NP_000607 Entrez Gene 12504 MouseEntrez Gene 24932 RatEntrez Gene 920 Human UniProt ID P01730
Background	CD4 Monoclonal Antibody: CD4 is a member of the immunoglobulin superfamily and is implicated as associative recognition element in MHC (Major Histocompatibility Complex) class II-restricted immune response. On T-lymphocytes, it defines the helper/inducer subset. The mature 55 kd CD4 protein consists of a 372 amino acid extracellular segment composed of four tandem immunoglobulin-like VJ regions. The CD4 molecule is a major receptor for human immunodeficiency virus (HIV), binding directly to the envelope glycoprotein gp120 on HIV, with the co-receptors being CCR5 or CXCR4. It has been shown that the V-like domains are critical for binding with HIV envelope gp120.
Synonyms	CD4mut
Reference Data
Protein Families	Adult stem cells, Druggable Genome, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transmembrane
Protein Pathways	Antigen processing and presentation, Cell adhesion molecules (CAMs), Hematopoietic cell lineage, Primary immunodeficiency, T cell receptor signaling pathway

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