MON1A Goat Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 2-4 ug/ml
Reactivity	Human
Host	Goat
Clonality	Polyclonal
Immunogen	The immunogen for Anti-ATG4A Antibody: Peptide with sequence TEENGTVNDQTFHC, from the internal region of the protein sequence according to NP_443168.2; NP_840054.1.
Formulation	Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	MON1 homolog A, secretory trafficking associated
Database Link	NP_115731 Entrez Gene 84315 Human UniProt ID Q86VX9
Background	Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed.This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Transcript variants that encode distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
Synonyms	SAND1
Note	This antibody is expected to recognize both reported isoforms (NP_443168.2; NP_840054.1)
Reference Data

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