CD247 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:2000
Reactivity	Human, Mouse
Modifications	Phospho-specific
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-CD3 ? (Phospho-Tyr142) Antibody: A synthesized peptide derived from human CD3 ? (Phospho-Tyr142)
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Immunogen affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	19 kDa
Gene Name	CD247 molecule
Database Link	NP_932170 Entrez Gene 12503 MouseEntrez Gene 919 Human UniProt ID P20963
Background	Defects in CD3D are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (T(-)/B(+)/NK(+) SCID) [MIM:608971]. A form of severe combined immunodeficiency (SCID), a genetically and clinically heterogeneous group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels.
Synonyms	CD3-ZETA; CD3H; CD3Q; CD3Z; IMD25; T3Z; TCRZ
Note	CD3 ? (Phospho-Tyr142) Antibody detects endogenous levels of total CD3 ? (Phospho-Tyr142)
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway

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