p95 NBS1 (NBN) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:2000
Reactivity	Human
Modifications	Phospho-specific
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-Phospho-Nibrin(Ser278) Antibody: A synthesized peptide derived from human Nibrin around the phosphorylation site of Sersine 278
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Immunogen affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	85 kDa
Gene Name	nibrin
Database Link	NP_002476 Entrez Gene 4683 Human UniProt ID O60934
Background	NBS1 is a member of the MRE11/RAD50 double-strand break repair complex. Involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. Mutation results in the Nijmegen breakage syndrome (NBS), an autosomal recessive chromosomal instability syndrome.
Synonyms	AT-V1; AT-V2; ATV; NBS; NBS1; P95
Note	Phospho-Nibrin(Ser278) Antibody detects endogenous levels of Nibrin only when phosphorylated at Sersine 278
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Homologous recombination

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