PERK (EIF2AK3) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:2000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-PERK Antibody: A synthesized peptide derived from human PERK
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Immunogen affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	125 kDa
Gene Name	eukaryotic translation initiation factor 2 alpha kinase 3
Database Link	NP_004827 Entrez Gene 13666 MouseEntrez Gene 29702 RatEntrez Gene 9451 Human UniProt ID Q9NZJ5
Background	Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis.
Synonyms	PEK; PERK; WRS
Note	PERK Antibody detects endogenous levels of total PERK
Reference Data
Protein Families	Druggable Genome, Protein Kinase, Secreted Protein, Transmembrane
Protein Pathways	Alzheimer's disease

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