Metabotropic Glutamate Receptor 5 (GRM5) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:1000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-GRM5 Antibody: A synthesized peptide derived from internal of human GRM5.
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Immunogen affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	120kd
Gene Name	glutamate metabotropic receptor 5
Database Link	NP_001137303 Entrez Gene 24418 RatEntrez Gene 108071 MouseEntrez Gene 2915 Human UniProt ID P41594
Background	G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current
Synonyms	GPRC1E; mGlu5; MGLUR5; PPP1R86
Note	GRM5 antibody detects endogenous levels of total GRM5 protein.
Reference Data
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	Calcium signaling pathway, Gap junction, Huntington's disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction

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