Bcl2 Binding component 3 (BBC3) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:2000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-BBC3(PUMA) Antibody: A synthesized peptide derived from human BBC3(PUMA)
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Immunogen affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	20 kDa
Gene Name	BCL2 binding component 3
Database Link	NP_055232 Entrez Gene 170770 MouseEntrez Gene 317673 RatEntrez Gene 27113 Human UniProt ID Q96PG8
Background	Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis. Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis
Synonyms	JFY-1; JFY1; PUMA
Note	BBC3(PUMA) Antibody detects endogenous levels of total BBC3(PUMA)
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Huntington's disease, p53 signaling pathway

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