MADH7 (SMAD7) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB 1/500
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-Smad7 Antibody: A synthesized peptide
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Immunogen affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	50KD
Gene Name	SMAD family member 7
Database Link	NP_005895 Entrez Gene 17131 MouseEntrez Gene 81516 RatEntrez Gene 4092 Human UniProt ID O15105
Background	Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access. Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex.
Synonyms	CRCS3; MADH7; MADH8
Note	Smad7 Antibody detects endogenous levels of total Smad7
Reference Data
Protein Families	Druggable Genome, Transcription Factors
Protein Pathways	TGF-beta signaling pathway

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