WASP (WAS) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:1000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-WASP Antibody: Peptide sequence around aa.289~293 (L-I-Y-D-F) derived from Human WASP.
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	53kd
Gene Name	Wiskott-Aldrich syndrome
Database Link	NP_000368 Entrez Gene 22376 MouseEntrez Gene 317371 RatEntrez Gene 7454 Human UniProt ID P42768
Background	Effector protein for Rho-type GTPases. Regulates actin filament reorganization via its interaction with the Arp2/3 complex. Important for efficient actin polymerization. Possible regulator of lymphocyte and platelet function. Mediates actin filament reorganization and the formation of actin pedestals upon infection by pathogenic bacteria.
Synonyms	IMD2; SCNX; THC; THC1; WASP; WASPA
Note	The antibody detects endogenous level of total WASP protein.
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Adherens junction, Chemokine signaling pathway, Fc gamma R-mediated phagocytosis, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton

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