CEBP Beta (CEBPB) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:2000
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-CEBPB Antibody: A synthesized peptide derived from human CEBPB
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Immunogen affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	49 kDa
Gene Name	CCAAT/enhancer binding protein beta
Database Link	NP_005185 Entrez Gene 12608 MouseEntrez Gene 1051 Human UniProt ID P17676
Background	The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.
Synonyms	C; EBP-beta; IL6DBP; NF-IL6; TCF5
Note	CEBPB Antibody detects endogenous levels of CEBPB
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Transcription Factors

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