TNFAIP8 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:2000
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-TFIP8 Antibody: A synthesized peptide derived from human TFIP8
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Immunogen affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	23 kDa
Gene Name	TNF alpha induced protein 8
Database Link	NP_055165 Entrez Gene 106869 MouseEntrez Gene 25816 Human UniProt ID O95379
Background	TNFAIP8 Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation. Belongs to the TNFAIP8 family. Induced by nuclear factor-KB (NF-KB) and TNF. Induction by TNF depends upon activation of NF-KB.
Synonyms	GG2-1; MDC-3.13; NDED; SCC-S2; SCCS2
Note	TFIP8 Antibody detects endogenous levels of TFIP8
Reference Data
Protein Families	Druggable Genome

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