MBD3 Rabbit Polyclonal Antibody

CAT#: TA347553

Rabbit Polyclonal Anti-MBD3 Antibody



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CNY 1,999.00

CNY 3,280.00


货期*
2周

规格
    • 100 ug

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Specifications

Product Data
Applications WB
Recommend Dilution WB: 1:500-1:3000
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen The immunogen for anti-MBD3 Antibody: A synthesized peptide derived from human MBD3
Formulation Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
Concentration lot specific
Purification Affinity-chromatography
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 33 kDa
Gene Name methyl-CpG binding domain protein 3
Background MBD3 methyl-CpG binding (MBD) proteins appear to bind differentially methylated domains (DMDs) of DNA, to recruit repression complexes, and to silence the locus. The methyl CpG binding domain of human MBD3 may not directly bind mCpG but does interact with the NuRD/Mi2 components HDAC1 and MTA2. Plays a role in histone deacetylation and nucleosome remodeling. Increased levels have been reported in lung cancer and glioblastomas and may be a therapeutic target.
Synonyms MBD3
Note MBD3 antibody detects endogenous levels of total MBD3
Reference Data
Protein Families Druggable Genome, Transcription Factors
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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