XPA Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:3000
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-XPA Antibody: A synthesized peptide derived from human XPA
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Affinity-chromatography
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	40 kDa
Gene Name	XPA, DNA damage recognition and repair factor
Database Link	NP_000371 Entrez Gene 22590 MouseEntrez Gene 7507 Human UniProt ID P23025
Background	XPA Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Required for UV-induced CHK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers (CPD), sites of DNA damage after UV irradiation.
Synonyms	XP1; XPAC
Note	XPA antibody detects endogenous levels of total XPA
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Nucleotide excision repair

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