TIMP3 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:3000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-TIMP3 Antibody: A synthesized peptide derived from human TIMP3
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Affinity-chromatography
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	25 kDa
Gene Name	TIMP metallopeptidase inhibitor 3
Database Link	NP_000353 Entrez Gene 21859 MouseEntrez Gene 25358 RatEntrez Gene 7078 Human UniProt ID P35625
Background	TIMP3 Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP1, MMP2, MMP3, MMP7, MMP9, MMP13, MMP14 and MMP15.
Synonyms	HSMRK222; K222; K222TA2; SFD
Note	TIMP3 antibody detects endogenous levels of total TIMP3
Reference Data
Protein Families	Druggable Genome, Secreted Protein

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