MCL1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:3000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-MCL1 Antibody: A synthesized peptide derived from human MCL1
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Affinity-chromatography
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	37 kDa,32 kDa
Gene Name	myeloid cell leukemia 1
Database Link	NP_068779 Entrez Gene 17210 MouseEntrez Gene 60430 RatEntrez Gene 4170 Human UniProt ID Q07820
Background	MCL1 a myeloid cell leukemia protein of the Bcl-2 family of proteins. Two alternatively spliced transcripts encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing.
Synonyms	bcl2-L-3; BCL2L3; EAT; Mcl-1; mcl1; MCL1-ES; MCL1L; MCL1S; TM
Note	MCL1 antibody detects endogenous levels of total MCL1
Reference Data
Protein Families	Druggable Genome, Transmembrane

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