IL2 Receptor beta (IL2RB) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:3000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-IL-2Rbeta/CD122 Antibody: A synthesized peptide derived from human IL-2Rbeta/CD122
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Affinity-chromatography
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	75 kDa
Gene Name	interleukin 2 receptor subunit beta
Database Link	NP_000869 Entrez Gene 16185 MouseEntrez Gene 25746 RatEntrez Gene 3560 Human UniProt ID P14784
Background	IL2RB Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. Belongs to the type I cytokine receptor family. Type 4 subfamily. Non-covalent dimer of an alpha and a beta subunit.
Synonyms	CD122; IL15RB; P70-75
Note	IL-2Rbeta/CD122 antibody detects endogenous levels of total IL-2Rbeta/CD122
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Cytokine-cytokine receptor interaction, Endocytosis, Jak-STAT signaling pathway

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