KMT5A Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western blotting (1:1,000)
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-SETD8 antibody: human SETD8 (SET domain containing 8), using the full length protein containing a Flag-tagged N-terminus and a His-tagged C terminus.
Concentration	lot specific
Purification	Protein G purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	lysine methyltransferase 5A
Database Link	NP_065115 Entrez Gene 67956 MouseEntrez Gene 387893 Human UniProt ID Q9NQR1
Background	SETD8 (UniProtKB/Swiss-Prot entry Q9NQR1) is a histone methyl transferase that specifically monomethylates 'Lys-20' of histone H4. This histone modification represents a specific tag for epigenetic transcriptional repression en is enriched during mitosis. SETD8 may also play a role in maintaining silent chromatin by preventing the acetylation of the H4 tail.
Synonyms	PR-Set7; SET07; SET8; SETD8
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Lysine degradation

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