RTF1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western blotting (1:1,000); Immunofluorescence (1:50); Immunoprecipitation (12 µg per IP); ChIP (1 - 5 µg per ChIP)
Reactivity	Drosophila
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-Rtf1 antibody: drosophila Rtf1 (Rtf1, Paf1/RNA polymerase II complex component, homolog), using the full length recombinant protein.
Concentration	lot specific
Purification	In solution in PBS including 0.05% azide and 0.05% ProClin 300. The polyclonal antibody has been protein G purified.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	RTF1 homolog, Paf1/RNA polymerase II complex component
Database Link	NP_055953 Entrez Gene 23168 Human UniProt ID Q92541
Background	PAF is a five-subunit protein complex composed of Paf1, Cdc73, Leo1, Rtf1 and Ctr9, which was first purified from yeast. The yeast PAF (yPAF) complex interacts with RNA polymerase II and coordinates the setting of histone marks associated with active transcription. The human PAF (hPAF) complex shares four subunits with yPAF (hCtr9, hPaf1, hLeo1 and Cdc73), but contains an additional higher eukaryotic-specific subunit, hSki8. In addition to coordinating events during transcription (initiation, promoter clearance and elongation); PAF also coordinates events in RNA quality control.
Synonyms	GTL7; KIAA0252
Reference Data

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