HP1 alpha (CBX5) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	ChIP (4ug/ChIP); Western blotting (1:1,000); IF (1:500)
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-HP1.,.,. antibody: human HP1 . (Heterochromatin protein 1 homolog beta), using the full length recombinant GST tagged protein. The antibody also recognizes the . and . isoforms.
Concentration	lot specific
Purification	Protein G purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	chromobox 5
Database Link	NP_036249 Entrez Gene 12419 MouseEntrez Gene 23468 Human UniProt ID P45973
Background	HP1 alpha, beta and gamma (UniProt/Swiss-Prot entry P45973, P83916 and Q13185) are components of heterochromatin. They recognize and bind histone H3 tails methylated at 'Lys-9', leading to epigenetic repression of transcription. HP1 alpha, beta and gamma also interact with lamin B receptor (LBR), thereby contributing to the association of heterochromatin with the inner nuclear membrane.
Synonyms	HEL25; HP1; HP1A
Reference Data

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