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RPA34 (RPA2) Mouse Monoclonal Antibody [Clone ID: 3E7-B5-F2]
CAT＃: TA347041S
Mouse Monoclonal RPA32/RPA2 Antibody
Size: 100 ul
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CNY 800.00
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Specifications
| Product Data | |
| Clone Name | 3E7-B5-F2 |
| Applications | IF, IP, WB |
| Recommend Dilution | WB: 1:2000, IF: 1:200 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Immunogen | The immunogen for RPA2 antibody: purified recombinant human RPA32/RPA2 protein fragments expressed in E.coli. |
| Formulation | Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol. |
| Purification | Affinity purified |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 32 kDa |
| Gene Name | replication protein A2 |
| Database Link | |
| Background | Required for DNA recombination,repair and replication.The activity of RP-A is mediated by single-stranded DNA binding and protein interactions.Required for the efficient recruitment of the DNA double-strand break repair factor RAD51 to chromatin in response to DNA damage.Functions as component of the alternative replication protein A complex (aRPA).aRPA binds single-stranded DNA and probably plays a role in DNA repair;it does not support chromosomal DNA replication and cell cycle progression through S-phase.In vitro,aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC),the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange. |
| Synonyms | REPA2; RP-A p32; RP-A p34; RPA32 |
| Reference Data | |
| Protein Families | Druggable Genome, Stem cell - Pluripotency |
| Protein Pathways | DNA replication, Homologous recombination, Mismatch repair, Nucleotide excision repair |
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