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AMPK beta 1 (PRKAB1) Mouse Monoclonal Antibody [Clone ID: 1A7-E11-E9]
CAT＃: TA347027S
Mouse Monoclonal AMPK beta 1 Antibody
Size: 100 ul
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CNY 800.00
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Specifications
| Product Data | |
| Clone Name | 1A7-E11-E9 |
| Applications | IF, IHC, IP, WB |
| Recommend Dilution | WB: 1:1000, IF: 1:100 |
| Reactivity | Human, Mouse, Rat, Monkey |
| Host | Mouse |
| Clonality | Monoclonal |
| Immunogen | The immunogen for PRKAB1 antibody: purified recombinant human AMPK beta 1 protein fragments expressed in E.coli. |
| Formulation | Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol. |
| Purification | Affinity purified |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 38 kDa |
| Gene Name | protein kinase AMP-activated non-catalytic subunit beta 1 |
| Database Link | |
| Background | The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK).AMPK is a heterotrimer consisting of an alpha catalytic subunit,and non-catalytic beta and gamma subunits.AMPK is an important energy-sensing enzyme that monitors cellular energy status.In response to cellular metabolic stresses,AMPK is activated,and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR),key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol.This subunit may be a positive regulator of AMPK activity.The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex. [provided by RefSeq,Jul 2008] |
| Synonyms | AMPK; HAMPKb |
| Reference Data | |
| Protein Families | Druggable Genome |
| Protein Pathways | Adipocytokine signaling pathway, Hypertrophic cardiomyopathy (HCM), Insulin signaling pathway |
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