PDHA1 Mouse Monoclonal Antibody [Clone ID: 3H2-F8-B5]

CAT#: TA347015S

Mouse Monoclonal pyruvate dehydrogenase (lipoamide) alpha 1 Antibody

Size: 20 ul 100 ul



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CNY 800.00


货期*
2周

规格
    • 20 ul

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Recombinant protein of human pyruvate dehydrogenase (lipoamide) alpha 1 (PDHA1), nuclear gene encoding mitochondrial protein, 20 µg
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Transient overexpression lysate of pyruvate dehydrogenase (lipoamide) alpha 1 (PDHA1), nuclear gene encoding mitochondrial protein, transcript variant 2
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Specifications

Product Data
Clone Name 3H2-F8-B5
Applications IF, WB
Recommend Dilution WB: 1:1000, IF: 1:100
Reactivity Human, Mouse
Host Mouse
Clonality Monoclonal
Immunogen The immunogen for PDHA1 antibody: purified recombinant human Pyruvate Dehydrogenase protein fragments expressed in E.coli.
Formulation Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50%,glycerol
Purification Affinity purified
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 43 kDa
Gene Name pyruvate dehydrogenase (lipoamide) alpha 1
Background The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms PDHA; PDHAD; PDHCE1A; PHE1A
Reference Data
Protein Families Druggable Genome
Protein Pathways Butanoate metabolism, Citrate cycle (TCA cycle), Glycolysis / Gluconeogenesis, Metabolic pathways, Pyruvate metabolism, Valine, leucine and isoleucine biosynthesis
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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