Hsp60 (HSPD1) Mouse Monoclonal Antibody [Clone ID: 6C8-G1-B10]

Specifications

Product Data
Clone Name	6C8-G1-B10
Applications	IF, IP, WB
Recommend Dilution	WB: 1:1000, IF: 1:100, IP: 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	The immunogen for HSP60 antibody: purified recombinant human Hsp60 protein fragments expressed in E.coli.
Formulation	Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
Purification	Affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	60 kDa
Gene Name	heat shock protein family D (Hsp60) member 1
Database Link	NP_002147 Entrez Gene 15510 MouseEntrez Gene 63868 RatEntrez Gene 3329 Human UniProt ID P10809
Background	This gene encodes a member of the chaperonin family.The encoded mitochondrial protein may function as a signaling molecule in the innate immune system.This protein is essential for the folding and assembly of newly imported proteins in the mitochondria.This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter.Several pseudogenes have been associated with this gene.Two transcript variants encoding the same protein have been identified for this gene.Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. [provided by RefSeq,Jun 2010]
Synonyms	CPN60; GROEL; HLD4; HSP-60; HSP60; HSP65; HuCHA60; SPG13
Reference Data
Protein Families	Druggable Genome, Stem cell - Pluripotency
Protein Pathways	RNA degradation, Type I diabetes mellitus

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