Histone H2A.X (H2AFX) Mouse Monoclonal Antibody [Clone ID: 7G9-H4]

Specifications

Product Data
Clone Name	7G9-H4
Applications	IF, WB
Recommend Dilution	WB: 1:2000, IF: 1:400
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	The immunogen for H2AX(Pi-Ser139) antibody: Synthetic phosphopeptide corresponding to residues surrounding Ser139 of human H2A.X.
Formulation	Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.03% Proclin300 and 50% glycerol.
Purification	Affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	H2A histone family member X
Database Link	NP_002096 Entrez Gene 15270 MouseEntrez Gene 3014 Human UniProt ID P16104
Background	Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.
Synonyms	H2A; H2A.X; H2AX; X
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Systemic lupus erythematosus

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