HP1 alpha (CBX5) Mouse Monoclonal Antibody [Clone ID: 3G2-H10-A6]
CAT#: TA346905
Mouse Monoclonal HP1 alpha Antibody
Size: 20 ul
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CNY 2,700.00
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Specifications
Product Data | |
Clone Name | 3G2-H10-A6 |
Applications | IF, IHC, WB |
Recommend Dilution | WB: 1:1000, IF: 1:300 |
Reactivity | Human, Mouse |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | The immunogen for CBX5 antibody: purified recombinant human HP1 alpha protein fragments expressed in E.coli. |
Formulation | Purified mouse monoclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50%,glycerol |
Purification | Affinity purified |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 26 kDa |
Gene Name | chromobox 5 |
Database Link | |
Background | This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
Synonyms | HEL25; HP1; HP1A |
Reference Data |
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