Aurora A (AURKA) Mouse Monoclonal Antibody [Clone ID: 2E3-C10-C11-G6]

Specifications

Product Data
Clone Name	2E3-C10-C11-G6
Applications	IF, WB
Recommend Dilution	WB: 1:500, IF: 1:50
Reactivity	Human, Monkey
Host	Mouse
Clonality	Monoclonal
Immunogen	The immunogen for AURKA antibody: purified recombinant human Aurora Kinase A protein fragments expressed in E.coli.
Formulation	ascites
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	46 kDa
Gene Name	aurora kinase A
Database Link	NP_940839 Entrez Gene 6790 Human UniProt ID O14965
Background	The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms	AIK; ARK1; AURA; BTAK; PPP1R47; STK6; STK7; STK15
Reference Data
Protein Families	Druggable Genome, Protein Kinase, Stem cell - Pluripotency
Protein Pathways	Oocyte meiosis

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