AMACR Mouse Monoclonal Antibody [Clone ID: 2F3-C11-B12]
CAT#: TA346883S
Mouse Monoclonal AMACR (C-terminus) Antibody
Size: 100 ul
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Specifications
Product Data | |
Clone Name | 2F3-C11-B12 |
Applications | IF, WB |
Recommend Dilution | WB: 1:1000, IF: 1:100 |
Reactivity | Rat |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | The immunogen for AMACR antibody: purified recombinant human AMACR(C-terminus) protein fragments expressed in E.coli. |
Formulation | Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50%,glycerol |
Purification | Affinity purified |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 42 kDa |
Gene Name | alpha-methylacyl-CoA racemase |
Database Link | |
Background | This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)-and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. |
Synonyms | AMACRD; CBAS4; RACE; RM |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Metabolic pathways, Primary bile acid biosynthesis |
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