Hex (HHEX) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB
Reactivity	Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-Hhex antibody: synthetic peptide directed towards the c terminal of mouse Hhex. Synthetic peptide located within the following region: SLDTSCEQGQDLPSEQNKGASLDRSQCSPSPASQEDPDSEISEDSDQEVD
Formulation	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	30 kDa
Gene Name	hematopoietically expressed homeobox
Database Link	NP_002720 Entrez Gene 15242 Mouse UniProt ID Q03014
Background	Hhex recognizesThe DNA sequence 5'-ATTAA-3'. Hhex is a transcriptional repressor.It may play a role in hematopoietic differentiation.Hhex establishes anterior identity at two levels; acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL.
Synonyms	HEX; HMPH; HOX11L-PEN; PRH; PRHX
Note	Immunogen Sequence Homology: Mouse: 100%; Pig: 92%; Guinea pig: 92%; Dog: 86%; Rat: 86%; Human: 86%; Rabbit: 86%; Horse: 85%; Bovine: 85%
Reference Data
Protein Families	Druggable Genome, Transcription Factors
Protein Pathways	Maturity onset diabetes of the young

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