LTBP4 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-LTBP4 antibody is: synthetic peptide directed towards the C-terminal region of Human LTBP4. Synthetic peptide located within the following region: GGPYGESEAPAPPGPGTRWPYRSRDTRRSFPEPEEPPEGGSYAGSLAEPY
Formulation	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	69 kDa
Gene Name	latent transforming growth factor beta binding protein 4
Database Link	NP_001036009 Entrez Gene 8425 Human UniProt ID Q8N2S1
Background	The protein encoded by this gene binds transforming growth factor beta (TGFB) as it is secreted and targeted to the extracellular matrix. TGFB is biologically latent after secretion and insertion into the extracellular matrix, and sheds TGFB and other proteins upon activation. Defects in this gene may be a cause of cutis laxa and severe pulmonary, gastrointestinal, and urinary abnormalities. Three transcript variants encoding different isoforms have been found for this gene.
Synonyms	ARCL1C; LTBP-4; LTBP4L; LTBP4S
Note	Immunogen Sequence Homology: Human: 100%; Bovine: 93%; Dog: 86%; Horse: 86%; Rabbit: 79%
Reference Data
Protein Families	Druggable Genome

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