IBP160 (AQR) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-AQR antibody is: synthetic peptide directed towards the C-terminal region of Human AQR. Synthetic peptide located within the following region: DTTPSETGATSTPEAIPALSETTPTVVGAVSAPAEANTPQDATSAPEETK
Formulation	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	171 kDa
Gene Name	aquarius intron-binding spliceosomal factor
Database Link	NP_055506 Entrez Gene 9716 Human UniProt ID O60306
Background	AQR is an intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. AQR plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. AQR may act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.
Synonyms	fSAP164; IBP160
Note	Immunogen Sequence Homology: Human: 100%; Horse: 79%
Reference Data
Protein Pathways	Spliceosome

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