DRP1 (DNM1L) Mouse Monoclonal Antibody [Clone ID: 4E11B11]
CAT#: TA336948
Mouse Monoclonal DRP1 Antibody (4E11B11)
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CNY 5,381.00
Cited in 3 publications. |
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 3,080.00
CNY 9,998.00
CNY 4,840.00
Specifications
Product Data | |
Clone Name | 4E11B11 |
Applications | ELISA, IHC, WB |
Recommend Dilution | Immunohistochemistry: 1:200 - 1:1000, Immunohistochemistry-Paraffin: 1:200 - 1:1000, Western Blot: 1:500 - 1:2000, ELISA: 1:10000 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Partial recombinant human DRP1 (between residues 100-250) expressed in E. coli. [UniProt O00429] |
Formulation | PBS, 0.03% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Concentration | lot specific |
Purification | Ammonium sulfate precipitation |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | dynamin 1-like |
Database Link | |
Background | A human dynamin-related protein, DRP1 contributes to mitochondrial division in mammalian cells. It plays this important role in mitochondrial fission at steady state and during apoptosis. DRP1 is required for proper cellular distribution of mitochondria, and in mutant neurons, mitochondria are largely absent from synapses, thus providing a genetic tool to assess the role of mitochondria at synapses. |
Synonyms | DLP1; DRP1; DVLP; DYMPLE; EMPF; EMPF1; HDYNIV |
Reference Data | |
Protein Pathways | Endocytosis, Fc gamma R-mediated phagocytosis |
Citations (3)
The use of this Antibodies has been cited in the following citations: |
---|
Drp1-dependent mitochondrial fission mediates osteogenic dysfunction in inflammation through elevated production of reactive oxygen species
,null,
PLoS ONE
,PubMed ID 28388678
[DNM1L]
|
The cyclophilin D/Drp1 axis regulates mitochondrial fission contributing to oxidative stress-induced mitochondrial dysfunctions in SH-SY5Y cells.
,null,
Biochemical and biophysical research communications
,PubMed ID 27993675
[DNM1L]
|
Reactive oxygen species regulatory mechanisms associated with rapid response of MC3T3-E1 cells for vibration stress.
,null,
Biochemical and biophysical research communications
,PubMed ID 26802466
[DNM1L]
|
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