Glucose 6 Phosphate Dehydrogenase (G6PD) Mouse Monoclonal Antibody [Clone ID: 2H7]

Specifications

Product Data
Clone Name	2H7
Applications	ELISA, FC, IHC, WB
Recommend Dilution	Flow Cytometry: 1:200-1:400, ELISA: 1:10000, Western Blot: 1:500-1:1000, Immunohistochemistry-Paraffin: 1:200-1:1000, Immunohistochemistry
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant fragment of human Glucose 6 Phosphate Dehydrogenase expressed in E. coli. [UniProt# P11413]
Formulation	PBS, 0.03% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Concentration	lot specific
Purification	Ammonium sulfate precipitation
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	59 kDa
Gene Name	glucose-6-phosphate dehydrogenase
Database Link	NP_000393 Entrez Gene 2539 Human UniProt ID P11413
Background	This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms	G6PD1
Note	This Glucose 6 Phosphate Dehydrogenase (2H7) antibody is useful for Western blot, Immunohistochemistry on paraffin-embedded sections, Flow Cytometry and ELISA.
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Glutathione metabolism, Metabolic pathways, Pentose phosphate pathway

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