VR1 (TRPV1) Rabbit Polyclonal Antibody

CAT#: TA336871

Rabbit Polyclonal Vanilloid R1/TRPV1 Antibody



Need it in bulk or conjugated?
Get a free quote

CNY 5,521.00


货期*
5周

规格
    • 100 ul

Cited in 4 publications.

Product images

经常一起买 (3)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

CNY 300.00
CNY 1,430.00


Transient overexpression lysate of transient receptor potential cation channel, subfamily V, member 1 (TRPV1), transcript variant 4
    • 100 ug

CNY 4,840.00


Transient overexpression lysate of transient receptor potential cation channel, subfamily V, member 1 (TRPV1), transcript variant 1
    • 100 ug

CNY 4,840.00

Specifications

Product Data
Applications IHC
Recommend Dilution Immunohistochemistry
Reactivity Human, Mouse, Rat, Primate
Host Rabbit
Clonality Polyclonal
Immunogen A synthetic peptide made to an N-terminal portion of the rat TRPV1 protein (between residues 1-50) [UniProt O35433]
Formulation PBS with 30% Glycerol, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Concentration lot specific
Purification Affinity purified
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name transient receptor potential cation channel subfamily V member 1
Background TRPV1 (transient receptor potential cation channel subfamily V member 1, capsaicin receptor, vanilloid receptor, Vr1) is a polymodal nociceptor activated by heat, vanilloids (capsaicin), and protons. It is primarily expressed in the dorsal root ganglia and peripheral nerve endings. TRPV1 antagonists are a potential therapeutic target for many suffering chronic physical and neuropathic pain. However, due to its other role in the regulation of body temperature, these therapies are currently experiencing a barrier. On the other hand, TRPV1 agonists can be used to desensitize nerves after activation, thereby reducing pain. The research around TRPV1 is broad, where it is studied in fields such as anxiety, pain, oxidative stress, taste, inflammation, depression, respiratory disease, and various psychiatric disorders.
Synonyms VR1
Note This TRPV1 antibody is useful for Western Blot and Immunocytochemistry/Immunofluorescence. In Western Blot, a band is seen ~100 kDa representing TRPV1. In ICC/IF, plasma membrane staining is observed in Ntera-2 cells. This antibody is not recommended for IHC-paraffin embedded sections.
Reference Data
Protein Families Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane
Protein Pathways Neuroactive ligand-receptor interaction
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (4)

Customer Reviews 
Loading...