HSP70-1A (HSPA1A) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, ICC/IF, IHC, Simple Western
Recommend Dilution	Flow Cytometry: 1 : 200, Immunocytochemistry/ Immunofluorescence: 1:25, Immunohistochemistry: 1:400, Immunohistochemistry-Paraffin: 1:400, Simple Western: 1:50, Immunohistochemistry-Frozen
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic peptide made to an internal portion of the human Hsp70 protein (between residues 550-600) [UniProt P08107]
Formulation	PBS, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Concentration	lot specific
Purification	Immunogen affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	heat shock protein family A (Hsp70) member 1A
Database Link	NP_005336 Entrez Gene 193740 MouseEntrez Gene 3303 Human UniProt ID P0DMV8
Background	Heat shock protein 70 1A/1B (also known as HSP70, HSPA1A, HSPA1B, HSP70 1/2) is a chaperone protein which can stabilize proteins against aggregation and assist in protein folding. It has been shown to play a role in aging, viral replication, lupus, and tumor progression. Accordingly, HSP70 has been used in anti-tumor vaccines, as well as HIV and Parkinson's research.
Synonyms	HEL-S-103; HSP70-1; HSP70-1A; HSP70.1; HSP70I; HSP72; HSPA1
Note	This Hsp70 antibody is useful for Immunocytochemistry/Immunofluorescence and IHC-paraffin embedded sections.
Reference Data
Protein Pathways	Antigen processing and presentation, Endocytosis, MAPK signaling pathway, Prion diseases, Spliceosome

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