VDAC2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western Blot: 1-3 ug/ml
Reactivity	Human, Bovine, Canine, Feline, Primate
Host	Rabbit
Clonality	Polyclonal
Immunogen	Amino acids 120-132 (KKSGKIKSSYKRE) of human VDAC2 protein were used as the immunogen.
Formulation	PBS containing 0.05% BSA, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Concentration	lot specific
Purification	Protein G purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	voltage dependent anion channel 2
Database Link	NP_003366 Entrez Gene 7417 Human UniProt ID P45880
Background	Voltage-dependent anion channels (VDAC) are small pore-forming membrane proteins that regulate metabolite exchange across the mitochondrial outer membrane. Apart from metabolite transfer, VDAC role has also been suggested during apoptosis. VDAC2 is one of the isoforms of VDAC. It interacts with BAK and functions as a specific inhibitor of BAK-dependent mitochondrial apoptosis.
Synonyms	POR
Reference Data
Protein Families	Druggable Genome, Ion Channels: Other
Protein Pathways	Calcium signaling pathway, Huntington's disease, Parkinson's disease

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