FOXP3 Rabbit Polyclonal Antibody

CAT#: TA336306

Rabbit Polyclonal FoxP3 Antibody



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CNY 6,188.00


货期*
5周

规格
    • 100 ul

经常一起买 (4)
Transient overexpression lysate of forkhead box P3 (FOXP3), transcript variant 1
    • 100 ug

CNY 4,840.00


beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

CNY 300.00
CNY 1,430.00


Recombinant protein of human forkhead box P3 (FOXP3), transcript variant 1, 20 µg
    • 20 ug

CNY 2,900.00


Recombinant protein of human forkhead box P3 (FOXP3), transcript variant 1, 100 µg
    • 100 ug

CNY 9,998.00

Specifications

Product Data
Applications FC, ICC/IF, IHC, Immunoblotting, IP, WB
Recommend Dilution Single Cell Western: 100 ug/mL, Western Blot: 1:2000, Flow Cytometry: 1:8000, Immunocytochemistry/ Immunofluorescence: 1:500, Immunoprecipitation, Immunohistochemistry-Paraffin: 1:400, Immunoblotting, Immunohistochemistry: 1:400, Dual RNAscope ISH-IHC
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen A peptide corresponding to amino acids 43-100 of mouse FOXP3. [Swiss-Prot# Q99JB6]
Formulation Tris-citrate/phosphate, pH 7, 0.1% Sodium azide. Store at 4C. Do not freeze.
Concentration lot specific
Purification Protein G purified
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name forkhead box P3
Background FOXP3 (a 381 amino acid protein) is a member of the forkhead/winged-helix family of transcriptional regulators and is highly conserved across mammals. FOXP3 is essential for normal immune homeostasis. FOXP3 is stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, a low level in CD4-positive/CD25-negative cells, and is absent in CD4-negative/CD8-positive T cells. FOXP3 may be a master regulatory gene and a more specific marker of regulatory T cells than other T cells.
Synonyms AIID; DIETER; IPEX; JM2; PIDX; XPID
Note This FOXP3 antibody can be used for Immunoprecipitation, Immunohistochemistry paraffin embeded sections and Western blot analysis, where a band is seen ~48 kDa in FOXP3 transfected and CD25/CD4 positive regulatory T cell lysates. In IP transfected FOXP3-HA tagged proteins were used. In IHC-P, staining was observed in the nuclei of mouse spleen cells. Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended.
Reference Data
Protein Families Transcription Factors
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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