VASP Rabbit Polyclonal Antibody

CAT#: TA333056

Phospho-VASP-S239 Rabbit Polyclonal Antibody



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CNY 2,700.00


货期*
2周

规格
    • 100 ul

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经常一起买 (4)
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Recombinant protein of human vasodilator-stimulated phosphoprotein (VASP), 20 µg
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Recombinant protein of human vasodilator-stimulated phosphoprotein (VASP), 100 µg
    • 100 ug

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Specifications

Product Data
Applications IHC, WB
Recommend Dilution WB 1:500 - 1:1000
Reactivity Human, Mouse, Rat
Modifications Phospho-specific
Host Rabbit
Clonality Polyclonal
Immunogen A phospho specific peptide corresponding to residues surrounding S239 of human VASP
Formulation PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 380
Gene Name vasodilator-stimulated phosphoprotein
Background Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.
Synonyms vasodilator-stimulated phosphoprotein
Reference Data
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways Fc gamma R-mediated phagocytosis, Focal adhesion, Leukocyte transendothelial migration
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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