Lamin B Receptor (LBR) Rabbit Polyclonal Antibody
CAT#: TA332706
Rabbit anti-LBR Polyclonal Antibody
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Specifications
Product Data | |
Applications | ICC/IF, WB |
Recommend Dilution | WB 1:500 - 1:2000 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human LBR |
Formulation | Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 615 |
Gene Name | lamin B receptor |
Database Link | |
Background | The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified. |
Synonyms | DHCR14B; LMN2R; PHA; TDRD18 |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
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