RIP2 (RIPK2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB 1:500 - 1:2000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant protein of human RIPK2
Formulation	Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration	lot specific
Purification	Affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	540
Gene Name	receptor interacting serine/threonine kinase 2
Database Link	NP_003812 Entrez Gene 192656 MouseEntrez Gene 362491 RatEntrez Gene 8767 Human UniProt ID O43353
Background	This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli.
Synonyms	CARD3; CARDIAK; CCK; GIG30; RICK; RIP2
Reference Data
Protein Families	Druggable Genome, Protein Kinase
Protein Pathways	Neurotrophin signaling pathway, NOD-like receptor signaling pathway

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