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PSMD2 Rabbit Polyclonal Antibody
CAT＃: TA332493S
Rabbit anti-PSMD2 Polyclonal Antibody
Size: 100 ul
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CNY 800.00
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Specifications
| Product Data | |
| Applications | ICC/IF, WB |
| Recommend Dilution | WB 1:500 - 1:2000;IF 1:50- 1:200 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human PSMD2 |
| Formulation | Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Concentration | lot specific |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 908 |
| Gene Name | proteasome 26S subunit, non-ATPase 2 |
| Database Link | |
| Background | The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. In addition to participation in proteasome function, this subunit may also participate in the TNF signalling pathway since it interacts with the tumor necrosis factor type 1 receptor. A pseudogene has been identified on chromosome 1. Alternative splicing results in multiple transcript variants of this gene. |
| Synonyms | P97; RPN1; S2; TRAP2 |
| Reference Data | |
| Protein Families | Druggable Genome |
| Protein Pathways | Proteasome |
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| 抗体相关资料 |
PSMD2 (Proteasome 26S S2) mouse monoclonal antibody, clone OTI1E7 (formerly 1E7), HRP conjugated
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PSMD2 (Proteasome 26S S2) mouse monoclonal antibody, clone OTI1G6 (formerly 1G6), Biotinylated
PSMD2 (Proteasome 26S S2) mouse monoclonal antibody, clone OTI1G6 (formerly 1G6), HRP conjugated
PSMD2 (Proteasome 26S S2) mouse monoclonal antibody, clone OTI1A12 (formerly 1A12), Biotinylated
PSMD2 (Proteasome 26S S2) mouse monoclonal antibody, clone OTI1A12 (formerly 1A12), HRP conjugated
PSMD2 (Proteasome 26S S2) mouse monoclonal antibody, clone OTI1B4 (formerly 1B4), Biotinylated
PSMD2 (Proteasome 26S S2) mouse monoclonal antibody, clone OTI1B4 (formerly 1B4), HRP conjugated
