Ornithine Decarboxylase (ODC1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ICC/IF, WB
Recommend Dilution	WB 1:500 - 1:2000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant protein of human ODC1
Formulation	Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration	lot specific
Purification	Affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	461
Gene Name	ornithine decarboxylase 1
Database Link	NP_002530 Entrez Gene 18263 MouseEntrez Gene 24609 RatEntrez Gene 4953 Human UniProt ID P11926
Background	Ornithine decarboxylase (ODC) is also named as ODC1and belongs to the Orn/Lys/Arg decarboxylase class-II family. It catalyzes the conversion of ornithine to putrescine, the first step and a major site of regulation of polyamine biosynthesis. The level of ODC is known to be controlled at several sites, namely transcription, translation, and enzyme degradation. Polyamines can stimulate the degradation of ODC as a type of negative feedback control(PMID:8486633). This protein can be phosphorylated in vivo(PMID:8798774). This antibody is specific to ODC1.
Synonyms	ODC
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Arginine and proline metabolism, Glutathione metabolism, Metabolic pathways

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