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GADD45A Rabbit Polyclonal Antibody
CAT＃: TA332434S
Rabbit anti-GADD45A Polyclonal Antibody
Size: 100 ul
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CN¥ 800.00
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Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommend Dilution | WB 1:500 - 1:2000 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human GADD45A |
| Formulation | PBS with 0.09% Sodium azide,50% glycerol,pH7.3. |
| Concentration | lot specific |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 18 kDa |
| Gene Name | growth arrest and DNA damage inducible alpha |
| Database Link | |
| Background | This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
| Synonyms | DDIT1; GADD45 |
| Reference Data | |
| Protein Families | Druggable Genome, Stem cell - Pluripotency |
| Protein Pathways | Cell cycle, MAPK signaling pathway, p53 signaling pathway |
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