GIPC (GIPC2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB 1:500 - 1:2000
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant protein of human GIPC2
Formulation	Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration	lot specific
Purification	Affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	315
Gene Name	GIPC PDZ domain containing family member 2
Database Link	NP_060125 Entrez Gene 54810 Human UniProt ID Q8TF65
Background	The eukaryotic PDZ domain is a multifunctional protein-protein interacting motif that is found in a variety of proteins and is involved in both the clustering of signaling molecules and the organization of protein networks. GIPC2 (GIPC PDZ domain containing family, member 2), also known as SEMCAP2, is a 315 amino acid protein that localizes to the cytoplasm and contains one PDZ domain. Expressed at high levels in kidney and colon and at lower levels in adult liver, GIPC2 interacts with SEMA5A and is thought to function as a scaffold protein, possibly modulating cell adhesion and growth factor signaling and playing a role in tumorigenesis. The gene encoding GIPC2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
Synonyms	SEMCAP-2; SEMCAP2
Reference Data

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