Aqp9 Rabbit Polyclonal Antibody
CNY 11,000.00
货期*
7周
规格
经常一起买 (1)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Applications | IHC, WB |
Recommend Dilution | WB: 1:200-1:2000; IHC: 1:100-1:3000 |
Reactivity | Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Peptide (C)EKDGAKKSLMQRLALK, corresponding to amino acid residues 4-19 of rat AQP-9. Intracellular, N-terminus. |
Formulation | Lyophilized. Concentration before lyophilization ~0.8mg/ml (lot dependent, please refer to CoA along with shipment for actual concentration). Buffer before lyophilization: Phosphate buffered saline (PBS), pH 7.4, 0.025% NaN3. |
Reconstitution Method | Add 50 ul double distilled water (DDW) to the lyophilized powder. |
Purification | Affinity purified on immobilized antigen. |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | aquaporin 9 |
Database Link | |
Background | Aquaporin 9 (AQP-9) belongs to a family of membrane proteins that allow passage of water and certain other solutes through biological membranes. The family is composed of 13 members (AQP-0 to AQP-12). Little is known about the function of the two newest members, AQP-11 and AQP-12. The aquaporins can be divided into two functional groups based on their permability characteristics: the aquaporins that are permeated primarily by water and include AQP-1, AQP-2, AQP4, AQP-5, AQP-6 and AQP-8, and the aquaglyceroporins that are permeated by water and other small solutes such as glycerol. This last group includes AQP-3, AQP-7, AQP-9 and AQP-10. The proteins present a conserved structure of six transmembrane domains with intracellular N- and C-termini. The functional channel is a tetramer but each subunit has a separate pore and therefore the functional channel unit contains four pores. AQP-9 is expressed in several tissues including brain, liver, testis and spleen. In the liver AQP-9 has a central role in glycerol metabolism as demonstrated in experiments using AQP-9 knockout mice: mice deficient in AQP-9 expression showed enhanced plasma levels of glycerol and triglycerides. |
Synonyms | AQP-9; HsT17287; SSC1 |
Reference Data |
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