PRC1 Mouse Monoclonal Antibody [Clone ID: 6G2]

Specifications

Product Data
Clone Name	6G2
Applications	WB
Recommend Dilution	WB
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Amino Acid: 1-150
Formulation	This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide at 0.5 mg/ml.
Concentration	lot specific
Purification	The antibody was purified by affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	72 kD
Gene Name	protein regulator of cytokinesis 1
Database Link	NP_955445 Entrez Gene 9055 Human UniProt ID O43663
Background	PRC1 (also known as protein regulator of cytokinesis 1 and mitotic spindle-associated CDK substrate) is a member of the MAP65/ASE1 family with a molecular weight of approximately 72 kD. PRC1 localization changes with cell-cycle position and can be found in the nucleus, the mitotic spindle, and the cell mid-body. PRC1 is a mitotic spindle-associated CDK substrate protein required for cytokinesis and maintenance of the spindle midzone. PRC1 can be modified by phosphorylation and has been shown to interact with Cdc2 and Cdk2. The 6G2 antibody recognizes the human PRC1 protein and has been shown to be useful for Western blotting.
Synonyms	ASE1
Reference Data

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