TIMP2 Mouse Monoclonal Antibody [Clone ID: F27P3A4]

Specifications

Product Data
Clone Name	F27P3A4
Applications	WB
Recommend Dilution	WB, IHC, ELISA
Reactivity	Human, Mouse, Rabbit, Chicken, Zebrafish, Pig, Porcine
Host	Mouse
Clonality	Monoclonal
Immunogen	Ovalbumin-conjugated synthetic Peptide DSGNDIYGNPI
Formulation	This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide at 0.5 mg/ml.
Concentration	lot specific
Purification	The antibody was purified by affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	24 kD
Gene Name	TIMP metallopeptidase inhibitor 2
Database Link	NP_003246 Entrez Gene 21858 MouseEntrez Gene 7077 Human UniProt ID P16035
Background	TIMP-2 (Tissue inhibitor of metalloproteinase 2) is a nonglycosylated protein that belongs to the protease inhibitor I35 (TIMP) family. Contains 1 NTR domain, predicted molecular weight 24 kD. The mechanisms of TIMPs inhibit angiogenesis appear to be specific for each member of the TIMP family. TIMP-2 binds to the surface of human endothelial cells through interaction with the integrin α3β1, and abrogates angiogenic factor induced endothelial cell proliferation in vitro and angiogenesis in vivo independent of MMP inhibition. Clone F27P3A4 has been shown to be useful for western blotting, immunohistochemistry and ELISA of human, mouse, rabbit, chicken, zebrafish, and pig TIMP-2.
Synonyms	CSC-21K; DDC8
Reference Data
Protein Families	Druggable Genome, Secreted Protein

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