MUM1 (IRF4) Rat Monoclonal Antibody [Clone ID: IRF4.3E4]

Specifications

Product Data
Clone Name	IRF4.3E4
Applications	WB
Recommend Dilution	WB, ICFC
Reactivity	Mouse, Human
Host	Rat
Clonality	Monoclonal
Immunogen	GST fusion protein containing C-terminal of murine IRF4
Formulation	Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Concentration	lot specific
Purification	The antibody was purified by affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	51 kD
Gene Name	interferon regulatory factor 4
Database Link	NP_002451 Entrez Gene 16364 MouseEntrez Gene 3662 Human UniProt ID Q15306
Background	The IRF family consists of at least nine members. IRF4 and IRF8 are highly homologous to each other and also redundant in function. IRF4 is critical for Th2 and Th17 development. Together with TRF8, it plays an essential role in macrophage and dendritic cell development and function. IRF4 is also reported to be essential for pre-B cell development, receptor editing, germinal center reactor and plasma cell differentiation.
Synonyms	LSIRF; MUM1; NF-EM5; SHEP8
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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