PPP2R2A Rabbit Polyclonal Antibody
CAT#: TA327323
Rabbit anti-PPP2R2A Polyclonal Antibody
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Specifications
Product Data | |
Applications | IHC, WB |
Recommend Dilution | WB 1:500 - 1:2000 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human PPP2R2A |
Formulation | Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | protein phosphatase 2 regulatory subunit Balpha |
Database Link | |
Background | Protein phosphatase 2A subunit B isoform R2-a (PPP2R2A) is the component of regulatory subunit B of serine/threonine protein phosphatase 2A (PP2A). PPP2R2A belongs to the R2/B55/PR55 family of regulatory subunit B. Evidence suggests that subunit PPP2R2A enhances TGF-β, Activin, and Nodal signaling pathways and may play an important role in cell cycle regulation. PPP2R2A/PP2A, B55-a/PR55-a isoform interacts with the type I TGF-β receptors via unique WD-40 repeats that contribute to the anti-proliferative function of TGF-β receptors. |
Synonyms | B55A; B55ALPHA; PR52A; PR55A |
Reference Data | |
Protein Families | Druggable Genome, Phosphatase |
Protein Pathways | Tight junction |
Documents
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