Piwil1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ICC/IF, IHC, WB
Recommend Dilution	WB: 1:500-1:2000;IF: 1:20-1:100
Reactivity	Mouse, Rat, Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant protein of mouse MIWI
Formulation	Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration	lot specific
Purification	Affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	piwi-like RNA-mediated gene silencing 1
Database Link	NP_067286 Entrez Gene 9271 HumanEntrez Gene 363912 RatEntrez Gene 57749 Mouse UniProt ID Q9JMB7
Background	The Drosophila piwi gene was identified as being required for the self-renewal of germline stem cells. Piwi homologs are well conserved among various species including Arabidopsis, C. elegans, and Homo sapiens. Both Miwi and Mili proteins are mouse homologs of Piwi and contain a C-terminal Piwi domain. Miwi and Mili bind to Piwi-interacting RNAs (piRNAs) in male germ cells and are essential for spermatogenesis in mice.
Synonyms	HIWI; MIWI; PIWI
Reference Data

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