STAR Rabbit Polyclonal Antibody

CAT#: TA326898

STAR Rabbit Polyclonal Antibody



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CNY 1,999.00

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货期*
2周

规格
    • 100 ul

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Specifications

Product Data
Applications IP, WB
Recommend Dilution WB 1:500 - 1:2000
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen Recombinant protein of human STAR
Formulation Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 32 kDa
Gene Name steroidogenic acute regulatory protein
Background Steroidogenic acute regulatory protein (StAR) plays a significant role in cholesterol transport from the cytoplasmic outer membrane to the inner mitochondrial membrane . The 37 kDa precursor is cleaved to generate an active 28 kDa protein capable of facilitating cholesterol metabolism into pregnenolone . StAR is prevalently expressed in mitochondria of steroid-producing adrenal and gonadal tissue . Abnormalities in StAR gene expression are impacted in autosomal Lipoid Congenial Adrenal Hyperplasia (LCAH) resulting in defects in pregnenolone and cortisol synthesis . The mechanism of cholesterol binding to StAR has yet to be elucidated .
Synonyms STARD1
Reference Data
Protein Families Druggable Genome
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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