STAR Rabbit Polyclonal Antibody
CNY 1,999.00
CNY 2,700.00
Product images
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 3,080.00
CNY 9,998.00
CNY 3,080.00
Specifications
Product Data | |
Applications | IP, WB |
Recommend Dilution | WB 1:500 - 1:2000 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human STAR |
Formulation | Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 32 kDa |
Gene Name | steroidogenic acute regulatory protein |
Database Link | |
Background | Steroidogenic acute regulatory protein (StAR) plays a significant role in cholesterol transport from the cytoplasmic outer membrane to the inner mitochondrial membrane . The 37 kDa precursor is cleaved to generate an active 28 kDa protein capable of facilitating cholesterol metabolism into pregnenolone . StAR is prevalently expressed in mitochondria of steroid-producing adrenal and gonadal tissue . Abnormalities in StAR gene expression are impacted in autosomal Lipoid Congenial Adrenal Hyperplasia (LCAH) resulting in defects in pregnenolone and cortisol synthesis . The mechanism of cholesterol binding to StAR has yet to be elucidated . |
Synonyms | STARD1 |
Reference Data | |
Protein Families | Druggable Genome |
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